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Research topics

Cardio-respiratory physiology is the central research field of PRETA which groups physiologists, emergency clinicians and experts in medical device conception and signal processing.

The primary purpose of the team is the development of tools and methods for the extraction of information from physiological and pathophysiological data (models and uses).
The transdisciplinary approach we develop allows us to overcome methodological barriers and to propose innovative preclinical and clinical tools. This strategy is based on both a strong investment in tools and skills in animal experiments experimental platform for small animal surgery, veterinary surgery on large mammals) and physiological investigation on healthy subjects (platform of investigation on healthy volunteers), and the search for additional solutions from the collaboration with different laboratories from other areas of research (physics, chemistry, etc ...).

Finally, PRETA continues to be involved in several basic research projects in different fields of physiology such as nutrition, cardiac ischemia and signal processing.

 

Team strength

 

  • Multidisciplinary team whose research areas lead to transdisciplinary projects
  • Development of tools and methods for extracting physiological information
  • Development of research with a high potential of valorization
  • Strong involvement of team members in teaching
Research Programs
Research Programs

During the evaluated period, the team has been involved in three basic research contracts (2 ANR contracts and 1 European FP7 contract) including 1 as principal investigator (ANR Blanc Sybecar project), 4 applied research projects (1 with the Direction Generale de l’Armement and 3 with the Institut de REcherche sur les Boissons) and 4 projects of valorization and transfer of technology (2 with Grenoble Alpes Valorisation Innovation Technologies, 1 with SATT GIFT and 1 with the Fonds Européen de Développement Régional).

Projet Breath-Diag

Supervisor(s): Raphaël BRIOT
Contract: AGENCE NATIONALE DE LA RECHERCHE (ANR-15-CE18-0006) - UNIVERSITE GRENOBLE ALPES - [2015-2019]
Fast and sensitive breath analysis for medical diagnostics.

Projet e-SwallHome

Swallowing and Respiration : Modelling and e-Health at Home
Supervisor(s): Pierre-Yves GUMERY
Contract: AGENCE NATIONALE DE LA RECHERCHE (ANR-13-TECS-0011) - UNIVERSITE GRENOBLE ALPES - [2014-2017]
The project aims to explain the normal behavior of two coupled functions in human, swallowing and breathing, to better understand the etiology of the mechanisms underlying pathological behaviors of dysphagia, dyspnea and dysphonia, related to a brain stroke.
Team members
Presentation of team members (introductory sentence)

Head :

Boucher F. (PU UGA)
Gumery P-Y. (PU UGA)

Permanent staff :

Anglade D. (PH CHUGA)
Briot R. (MCUPH UGA)
Brouta A. (Adj. UGA 80%)
Calabrèse-Vinot P. (MCF UGA)
Debaty G. (PH CHUGA)
Frikha R. (MCF VetAgro Sup)
Fontecave-Jallon J. (MCF UGA)
Loiacono P. (Adj. UGA 10%)
Tanguy S. (MCF UGA)
Thiebault J-J. (MCF VetAgro Sup)

 

2 free collaborators

1 Engineers

3 PhD students

Team coordinator(s)

Permanent members

PhD students

Platforms - Resources
PHYSIOLOGIE INTÉGRATIVE

 

Plateforme de Prestation en Physiologie Intégrative sur Volontaires Sains

 

Analyseur de gaz respiratoires

P3I

 

P3I

Monitoring non-invasif de la pression artérielle

P3I

ECG et sons cardiaques foetaux

P3I

Electroglottographie

P3I

Ceintures thoraciques multi-capteurs

P3I

Pléthysmographie Respiratoire par Inductance

P3I

Pneumotachographe

P3I

Cardio-Impédancemétrie

 

CHUGA

Localisation : Pavillon Taillefer (Site santé - CHUGA)

Responsables scientifiques : Julie Fontecave-Jallon et Pascale Calabrese

* Autorisations CPP 15/01/2014 et ANSM 29/01/2014
* Protocole ouvert (MAPO-RCVQ, 2013-A01560-45)

 

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PLATEAU PETIT ANIMAL

 

Plateau Petit Animal

 

  • Chirurgie expérimentale
  • Monitoring cardio-vasculaire par des méthodes invasives : mesures directes de pressions et débits
PPA PPA PPA

Monitoring cardio-respiratoire non-invasive par pléthysmographie (DECRO®).

PPA

Localisation : Bâtiment Jean Roget (UGA - Site Santé)

Responsable scientifique : Stéphane Tanguy

 

Primary collaborations and grants
  • Spectrometry laboratory of Joseph Fourier University - Grenoble (LIPhy UMR 5588, CNRS-UJF)

  • Laboratory of Basic and applied Bioenergetics of Joseph Fourier University - Grenoble (INSERM 1055)

  • Department of Physiology – Functional investigations, Raymond Poincaré hospital, AP-HP, Garches

  • Department of Pharmacology, Health Science Centre, University of Debrecen, Hungary

Contact

Address: TIMC-IMAG laboratory, Pavillon TAILLEFER, 38706 LA TRONCHE CEDEX - FRANCE