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Hybrid Modelling in Oncology: Sucesses, Challenges and Hopes

Angélique Stéphanou 1 Pascal Ballet 2 Gibin Powathil
1 TIMC-IMAG-DyCTiM - Dynamique Cellulaire et Tissulaire- Interdisciplinarité, Modèles & Microscopies
TIMC-IMAG - Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525
2 Lab-STICC_UBO_CID_IHSEV
Lab-STICC - Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance
Abstract : In this review we make the statement that hybrid models in oncology are required as a mean for enhanced data integration. In the context of systems oncology, experimental and clinical data need to be at the heart of the models developments from conception to validation to ensure a relevant use of the models in the clinical context. The main applications pursued are to improve diagnosis and to optimize therapies.We first present the Successes achieved thanks to hybrid modelling approaches to advance knowledge, treatments or drug discovery. Then we present the Challenges than need to be addressed to allow for a better integration of the model parts and of the data into the models. And Finally, the Hopes with a focus towards making personalised medicine a reality. Mathematics Subject Classification. 35Q92, 68U20, 68T05, 92-08, 92B05.
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Pré-publication, Document de travail
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https://hal.archives-ouvertes.fr/hal-01980757
Contributeur : Angélique Stéphanou <>
Soumis le : lundi 14 janvier 2019 - 16:18:36
Dernière modification le : jeudi 21 mars 2019 - 14:56:10

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  • HAL Id : hal-01980757, version 1
  • ARXIV : 1901.05652

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Angélique Stéphanou, Pascal Ballet, Gibin Powathil. Hybrid Modelling in Oncology: Sucesses, Challenges and Hopes. 2019. ⟨hal-01980757⟩

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