Fabien
Pierrel

Chercheur
Equipe GEM
[info]
Tél : 04 76 63 74 79
Adresse : Bâtiment Jean Roget, Domaine de la Merci
Bureau : 508E
Mots-clés

microorganismes, métabolisme, bioénergétique, évolution, quinones, ubiquinone, chaines respiratoires

Publications

Liste complète des publications:

http://www.researcherid.com/rid/M-6016-2014

 

Publications sélectionnées :

 

Ubiquinone Biosynthesis over the Entire O2 Range: Characterization of a Conserved O2-Independent Pathway

 

Pelosi, L., Vo, C. D., Abby, S. S., Loiseau, L., Rascalou, B., Hajj Chehade, M., Faivre, B., Gousse, M., Chenal, C., Touati, N., Binet, L., Cornu, D., Fyfe, C. D., Fontecave, M., Barras, F., Lombard, M.*, Pierrel, F*.

mBio (2019) 10: e01319-19        

DOI: 10.1128/mBio.01319-19

               

A soluble metabolon synthesizes the isoprenoid lipid Ubiquinone

Hajj Chehade, M., Pelosi, L., Fyfe, C., Loiseau, L., Rascalou, B., Brugiere, S., Kazemzadeh, K., Vo, T. D., Ciccone, L., Aussel, L., Coute, Y., Fontecave, M., Barras, F., Lombard, M. & Pierrel, F. *

Cell Chemical Biology (2019) 26:482-492

DOI: 10.1016/j.chembiol.2018.12.001

 

Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency.

Pierrel F.*

Front Physiol. (2017) 8:436

DOI: 10.3389/fphys.2017.00436

 

Evolution of Ubiquinone Biosynthesis: Multiple Proteobacterial Enzymes with Various Regioselectivities To Catalyze Three Contiguous Aromatic Hydroxylation Reactions

Pelosi L., Ducluzeau A. L., Loiseau L., Barras F., Schneider D., Junier I., Pierrel F.*

mSystems (2016) 1: e00091-16

DOI: 10.1128/mSystems.00091-16

 

Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast

Payet L. A., Leroux M., Willison J. C., Kihara A., Pelosi L., Pierrel F. *

Cell Chemical Biology (2016) 23: 1241-1250

DOI: 10.1016/j.chembiol.2016.08.008

 

 

 

Partenariats

Collaborations actives:

Marc Fontecave (Collège de France, Paris)

Frédéric Barras (Institut Pasteur, Paris)

Axel Magalon (LCB, Marseille)

Barbara Schoepp-Cothenet (BIP, Marseille)

Léonardo Salviati (Université de Padova, Italie)

Martin Ott (Stockholm University, Suède)