Research in BCM is done along three main axes : genomics, systems biology, and mathematical modeling of complex biological systems.
Methodology in computational biology is one of the main objectives
of BCM. Our research team develops new methods and algorithms
allowing us to validate or to choose computational or mathematical
models that can realistically account for the complexity of
biological data. Here, computational methods are inference
methods that make use of algorithmic principles or simulation
techniques. Applications to evolutionary genetics, genomics and
epidemiology are important aspects of our activity, that inspire most of the theoretical approaches developed in the team.
A non-limiting list of projects developed at BCM includes :
Genomics and evolutionary genetics.
Population genetic structure.
Inference of natural selection in human genomes.
Bayesian methods and machine learning.
Dynamics of genetic networks.
Formal methods for network modeling.
Mathematics of interacting particle systems.
Gene and species tree models.
Computer algorithms and stochastic simulation.