Aims : to develop innovative approaches for the exploration of biological tissues
Paradigm : Microscopy imaging as a revelatory of in situ molecular information (interactions and dynamics) and structural organization of tissues and organs
Methods : Modelling of image formation in biological tissues, modelling of the spatial and dynamic organization in relationship with the biological functions

Main development axes :
development of specimen preparation and standardization for qualitative and quantitative analysis
instrument development in microscopy and mesoscopy
development of tools for the modelling of large population of cells
These developments are driven in the frame of fundamental biological studies and for diagnosis and prognosis in medicine.
Scientific axes :
Characterization of tumoral tissues : proliferation and tumoral markers – quantitative microscopy – cellular sociology modelling – molecular network modelling
Engineering for biophotonics : development of new methods of microscopy (instruments and algorithms), development of mathematical and mechanical models for histology and cytology (cartography of the developing myocardium)