Research in BCM is done along three main axes : genomics, systems biology, and mathematical modeling of complex biological systems.
Methodology in computational biology is one of the main objective
of BCM. Our research team develops new methods and algorithms
allowing us to validate or to choose computer or mathematical
models that can realistically account for the complexity of
biological data. Here, computational methods are inference
methods that make use of algorithmic principles or simulation
techniques. Applications to evolutionary genetics, genomics and
epidemiology are important aspects of our activity, that inspire most of the theoretical approaches developed in the team.
A non-limiting list of projects developed at BCM includes :
Genomics and evolutionary genetics
Population genetic structure
Inference of natural selection in human genomes.
Bayesian methods and machine learning.
Smart pooling of protein-protein interactions.
Dynamics of genetic networks
Formal methods for network modeling
Mathematics of interacting particle systems
Gene and species tree models
Computer algorithms and stochastic simulation