Publications

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1- M-C. Toufektsian, S. Morel, S. Tanguy, A. Jeunet, J. de Leiris, F. Boucher. (2003) Involvement of reactive oxygen species in cardiac preconditioning in rats. Antioxidants & Redox Signaling 5:115-122.

2- S. Tanguy, S. Besse, V. Ducros, J. de Leiris, F. Boucher. (2003) Effect of increased dietary selenium intake on blood and cardiac selenium status during aging in rats. Nutrition Research. 23:239-243.

3- S. Tanguy, J. de Leiris, S. Besse, F. Boucher. (2003) Ageing exacerbates the cardiotoxicity of hydrogen peroxide through the Fenton reaction in rats. Mechanisms of Ageing & Development. 124:235-241.

4- S. Tanguy, M-C. Toufektsian, S. Besse, V. Ducros, J de Leiris, F Boucher. (2003) Dietary selenium intake affects cardiac susceptibility to ischemia/reperfusion in male senescent rats. Age & Ageing. 32:273-278.

5- S. Morel, S. Tanguy, M-C Toufektsian, C. Berthonneche, T Foulon, M de Lorgeril, J. de Leiris, F. Boucher. (2003) Insulin resistance modifies plasma fatty acid distribution and decreases cardiac tolerance to in vivo ischaemia/reperfusion in rats.Clinical & Experimental Pharmacology & Physiology. 30(7):446-451.

6- M. de Lorgeril, P. Salen, A. Guiraud, F. Boucher, J. de Leiris. (2003) Resveratrol and non-ethanolic components of wine in experimental cardiology. Nutrition Metabolism & Cardiovascular Diseases. 13(2):100-103.

7- A. Rakotovao, C. Berthonneche, A. Guiraud, M. de Lorgeril, P. Salen, J. de Leiris, F. Boucher. (2004) Ethanol, Wine and Experimental Cardioprotection in ischemia/reperfusion : Role of the prooxidant/antioxidant balance. Antioxidants & Redox Signaling. 6:431-438.

8- A. Guiraud, M. de Lorgeril, F. Boucher, C. Berthonneche, A. Rakotovao, J. de Leiris. (2004) Cardioprotective effect of chronic low dose ethanol drinking : Insights into the Concept of Ethanol Preconditioning. Journal of Molecular & Cellular Cardiology. 36:561-566.

9- S. Tanguy, S. Morel, C. Berthonneche, M-C Toufektsian, M. de Lorgeril, V. Ducros, A. Tosaki, J. de Leiris, F. Boucher. (2004) Pre-ischemic selenium status as a major determinant of myocardial infarct size in vivo in rats. Antioxidants & Redox Signaling. 6(4):792-796.

10- C. Berthonneche, T. Sulpice, F. Boucher, L. Gouraud, J. de Leiris, S.E. O’Connor, J-M. Herbert, P. Janiak. (2004) New insights into the pathological role of TNF- in early cardiac dysfunction and subsequent heart failure following myocardial infarction in rats. American Journal of Physiology. 287:H340-H350.

11- M.E. Szabo, E. Gallyas, I. Bak, A. Rakotovao, F. Boucher, J. de Leiris, N. Nagy, E. Varga, A. Tosaki. (2004) Heme oxygenase-1-related carbon monoxide and flavonoids in ischemic/reperfused rat retina. Investigative Ophthalmology & Visual Science. 45:3727-3732.

12- S. Besse, S. Tanguy, F. Boucher, C. Le Page, S. Rozenberg, B. Riou, J. de Leiris, and B. Swynghedauw. (2004) Cardioprotection with cariporide, a sodium-proton exchanger inhibitor, after prolonged ischemia and reperfusion in senescent rats. Experimental Gerontology. 39:1307-1314.

13- S. Morel, C. Berthonneche, S. Tanguy, M-C Toufektsian, J. de Leiris, F. Boucher. (2005) Early pre-diabetic state alters adaptation of myocardial metabolism during ischemia in rats. Molecular & Cellular Biochemistry. 272:9-17.

14- M. de Lorgeril, P. Salen, A. Guiraud, S. Zeghichi, F. Boucher, J. de Leiris. (2005) Lipid lowering drugs and essential omega-6 and omega-3 fatty acids in patients with coronary heart disease. Nutrition Metabolism & Cardiovascular Diseases. 15:36-41.

15- A. Rakotovao, S. Tanguy, M-C Toufektsian, C. Berthonneche, V. Ducros, A. Tosaki, J. de Leiris, F. Boucher. (2005) Selenium status as determinant of Connexin-43 dephosphorylation in ex-vivo ischemic/reperfused rat myocardium. Journal of Trace Elements in Medicine & Biology. 19:43-47.

16- C. Berthonneche, T. Sulpice, S. Tanguy, S.E. O’Connor, J-M. Herbert, P. Janiak, J. de Leiris, F. Boucher. (2005) AT1 receptor-blockade prevents cardiac dysfunction and remodeling and limits TNF- generation early after myocardial infarction in rats. Cardiovascular Drugs & Therapy. 19:251-259.

17- S. Besse, S. Tanguy, F. Boucher, C. Huraux, B. Riou, B. Swynghedauw, J. de Leiris. (2006) Protection of endothelial-derived vasorelaxation with cariporide, a sodium-proton exchanger inhibitor, after prolonged hypoxia and hypoxia-reoxygenation : effect of age. European Journal of Pharmacology. 531:187-193.

18- S. Rozenberg, B. Tavernier, B. Riou, B. Swynghedauw, C. Lepage, F. Boucher, J. de Leiris, S. Besse. (2006) Severe impairment of ventricular compliance accounts for advanced age-associated hemodynamic dysfunction in rats. Experimental Gerontology. 41(3):289-295.

19- J. de Leiris, M. de Lorgeril, F. Boucher. (2006) Editorial Focus : Ethanol and cardiac function. American Journal of Physiology 291:H1027-H1028.

20- I. Bak, I. Lekli, B. Juhasz, N. Nagy, E. Varga, J. Varadi, R. Gesztelvi, S. Szabo, L. Szendrei, I. Bacskay, M. Vecsernyes, N. Antal, L. Fesus, F. Boucher, J. de Leiris, A. Tosaki. (2006) Cardioprotective mechanisms of Prunus cerasus (sour cherry) seed extract against ischemia-reperfusion-induced damage in isolated rat hearts. American Journal of Physiology 291:H1329-H1336.

21- J. de Leiris, A. Rakotovao, F. Boucher. (2006) Oxidative stress and ischemia. Heart & Metabolism. 31:1-3.

22- S. Besse, A-L. Bulteau, F. Boucher, B. Riou, B. Swynghedauw, J. de Leiris. (2006) Antioxidant treatment prevents cardiac protein oxidation after ischemia-reperfusion and improves myocardial function and coronary perfusion in senescent hearts. Journal of Physiololgy & Pharmacology 57(4):541-552.

23- C. Berthonneche, M-C. Toufektsian, S. Tanguy, C. Ghezzi, J. de Leiris, F. Boucher. (2007) Does nitric oxide contribute to progressive cardiac tissue damage and dysfunction after infarction ? Antioxidants & Redox Signaling 9(6):757-763.

24- C. Moro, MG Jouan, A. Rakotovao, MC Toufektsian, O. Ormezzano, N. Nagy, A. Tosaki, J. de Leiris, F. Boucher. (2007) Delayed expression of cytokines after reperfused myocardial infarction : possible trigger for cardiac dysfunction and ventricular remodelling. American Journal of Physiology 293:H3014-H3019.

25- M. de Lorgeril, P. Salen, J-L. Martin, A. Guiraud, S. Zeghichi, F. Boucher, J. de Leiris. (2008) Interactions of wine drinking with omega-3 fatty acids in patients with coronary heart disease :A fish-like effect of moderate drinking. American Heart Journal 155(1):175-181.

26- F. Boucher, M-G Jouan, C. Moro, A. Rakotovao, S. Tanguy, J. de Leiris. (2008) Does selenium exert cardioprotective effects against oxidative stress in myocardial ischemia. Acata Physiologocia Hungarica 95(2):187-194.

27- MC Toufektsian, M de Lorgeril, N Nagy, P Salen, MB Donati, L Giordano, HP Mock, S Peterek, A Matros, K Petroni, R Pilu, D Rotilio, C Tonelli, J de Leiris, F. Boucher, C Martin. (2008) Protection against myocardial infarction after long-term Chronic dietary intake of plant-derived anthocyanins protects the rat heart against ischemia-reperfusion injury. Journal of Nutrition. 138:747-752. PMID : 18356330

28- J. de Leiris, M-G. Jouan, F. Boucher (2008) Effets bénéfiques du vin sur la santé : mythe ou réalité ? Vin & Santé 13 : 24-31.

29- A. Guiraud, M. de Lorgeril, S. Zeghichi, F. Laporte, P. Salen, V. Saks, N. Berraud, F. Boucher, J. de Leiris. (2008) Interactions of ethanol drinking with n-3 fatty acids in rats. Potential consequences for the cardiovascular system. British Journal of Nutrition. 100(6):1237-1244. PMID : 18445308

30- MC. Toufektsian, V. Robbez-Masson, DS Sanou, MG. Jouan, O. Ormezzano, J. de Leiris, F. Boucher. (2008) A single i.v. sTNFR-Fc administration at the time of reperfusion limits infarct size - implications in reperfusion strategies in man. Cardiovascular Drugs & Therapy. 22(6):437-442.

31- J. de Leiris, F. Boucher. (2008) Does wine consumption explain the French paradox ? Dialogues in Cardiovascular Medicine. 13(3):183-192.

32- J. de Leiris, F. Boucher (2009) The “French paradox” : a concept which has not finished making it self talked about (sous presse).

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